33,611 research outputs found

    A Note on Positive Energy Theorem for Spaces with Asymptotic SUSY Compactification

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    We extend the positive mass theorem proved previously by the author to the Lorentzian setting. This includes the original higher dimensional positive energy theorem whose spinor proof was given by Witten in dimension four and by Xiao Zhang in dimension five

    On data skewness, stragglers, and MapReduce progress indicators

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    We tackle the problem of predicting the performance of MapReduce applications, designing accurate progress indicators that keep programmers informed on the percentage of completed computation time during the execution of a job. Through extensive experiments, we show that state-of-the-art progress indicators (including the one provided by Hadoop) can be seriously harmed by data skewness, load unbalancing, and straggling tasks. This is mainly due to their implicit assumption that the running time depends linearly on the input size. We thus design a novel profile-guided progress indicator, called NearestFit, that operates without the linear hypothesis assumption and exploits a careful combination of nearest neighbor regression and statistical curve fitting techniques. Our theoretical progress model requires fine-grained profile data, that can be very difficult to manage in practice. To overcome this issue, we resort to computing accurate approximations for some of the quantities used in our model through space- and time-efficient data streaming algorithms. We implemented NearestFit on top of Hadoop 2.6.0. An extensive empirical assessment over the Amazon EC2 platform on a variety of real-world benchmarks shows that NearestFit is practical w.r.t. space and time overheads and that its accuracy is generally very good, even in scenarios where competitors incur non-negligible errors and wide prediction fluctuations. Overall, NearestFit significantly improves the current state-of-art on progress analysis for MapReduce

    An HMM-based Comparative Genomic Framework for Detecting Introgression in Eukaryotes

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    One outcome of interspecific hybridization and subsequent effects of evolutionary forces is introgression, which is the integration of genetic material from one species into the genome of an individual in another species. The evolution of several groups of eukaryotic species has involved hybridization, and cases of adaptation through introgression have been already established. In this work, we report on a new comparative genomic framework for detecting introgression in genomes, called PhyloNet-HMM, which combines phylogenetic networks, that capture reticulate evolutionary relationships among genomes, with hidden Markov models (HMMs), that capture dependencies within genomes. A novel aspect of our work is that it also accounts for incomplete lineage sorting and dependence across loci. Application of our model to variation data from chromosome 7 in the mouse (Mus musculus domesticus) genome detects a recently reported adaptive introgression event involving the rodent poison resistance gene Vkorc1, in addition to other newly detected introgression regions. Based on our analysis, it is estimated that about 12% of all sites withinchromosome 7 are of introgressive origin (these cover about 18 Mbp of chromosome 7, and over 300 genes). Further, our model detects no introgression in two negative control data sets. Our work provides a powerful framework for systematic analysis of introgression while simultaneously accounting for dependence across sites, point mutations, recombination, and ancestral polymorphism
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